Title | Anthryl-doped conjugated polyelectrolytes as aggregation-based sensors for nonquenching multicationic analytes. |
Publication Type | Journal Article |
Year of Publication | 2007 |
Authors | Satrijo, A, Swager, TM |
Journal | Journal of the American Chemical Society |
Volume | 129 |
Pagination | 16020–8 |
Date Published | dec |
ISSN | 1520-5126 |
Keywords | Cations, Electrolytes, Electrolytes: chemistry, Fluorescence, Spectrometry, Static Electricity |
Abstract | The fluorescence-based detection of nonquenching, multicationic small molecules has been demonstrated using a blue-emitting, polyanionic poly(p-phenylene ethynylene) (PPE) doped with green-emitting exciton traps (anthryl units). Multicationic amines (spermine, spermidine, and neomycin) were found to effectively induce the formation of tightly associated aggregates between the polymer chains in solution. This analyte-induced aggregation, which was accompanied by enhanced exciton migration in the PPE, ultimately led to a visually noticeable blue-to-green fluorescence color change in the solution. The aggregation-based sensor exhibited poor sensitivity toward dicationic and monocationic amines, demonstrating that a conjugated polyelectrolyte sensor relying on nonspecific, electrostatic interactions may still attain a certain level of selectivity. |
URL | http://www.ncbi.nlm.nih.gov/pubmed/18047336 |
DOI | 10.1021/ja075573r |