Poly(arylene ethynylene)s in chemosensing and biosensing.

TitlePoly(arylene ethynylene)s in chemosensing and biosensing.
Publication TypeJournal Article
Year of Publication2005
AuthorsZheng, J, Swager, TM
JournalAdvances in Polymer Science
Keywordsreview poly arylene ethynylene chemosensing biosensing

A review. Poly(arylene ethynylene)s (PArEs) have been used in recent years as effective transducers for a variety of sensing purposes ranging from org. mols. such as Me viologen and TNT to biol. analytes. Their superior sensitivity to minor perturbations is fundamentally governed by the energy transport properties resulting from the extended conjugation of the polymer backbone. An understanding of the underlying principles of energy transport allows the design of sensors with greater sensitivity and specificity. Pioneering work with Me viologen as an electron-transfer quencher demonstrated that connecting receptors in series amplifies the sensing response compared to that of individual receptors. Since then, factors such as the electronic and structural nature of the polymers and their assembly architecture have proven to be important in improving sensory response. In this review, the authors present an overview of works to date by various groups in the field of PArE chemosensors and biosensors. [on SciFinder(R)]