Water-soluble cationic conjugated polymers: response to electron-rich bioanalytes.

TitleWater-soluble cationic conjugated polymers: response to electron-rich bioanalytes.
Publication TypeJournal Article
Year of Publication2013
AuthorsRochat, S, Swager, TM
JournalJournal of the American Chemical Society
Volume135
Pagination17703–6
Date Publishednov
ISSN1520-5126
Keywordscationic conjugated polymer detn electron rich bio
Abstract

We report the concise synthesis of a symmetrical monomer that provides a head-to-head pyridine building block for the preparation of cationic conjugated polymers. The obtained poly(pyridinium-phenylene) polymers display appealing properties such as high electron affinity, charge-transport upon n-doping, and optical response to electron-donating analytes. A simple assay for the optical detection of low micromolar amounts of a variety of analytes in aqueous solution was developed. In particular, caffeine could be measured at a 25 $μ$M detection limit. The reported polymers are also suitable for layer-by-layer film formation.

URLhttp://www.ncbi.nlm.nih.gov/pubmed/24245751
DOI10.1021/ja4095395