Water-soluble cationic conjugated polymers: response to electron-rich bioanalytes.

TitleWater-soluble cationic conjugated polymers: response to electron-rich bioanalytes.
Publication TypeJournal Article
Year of Publication2013
AuthorsRochat, S, Swager, TM
JournalJournal of the American Chemical Society
Date Publishednov
Keywordscationic conjugated polymer detn electron rich bio

We report the concise synthesis of a symmetrical monomer that provides a head-to-head pyridine building block for the preparation of cationic conjugated polymers. The obtained poly(pyridinium-phenylene) polymers display appealing properties such as high electron affinity, charge-transport upon n-doping, and optical response to electron-donating analytes. A simple assay for the optical detection of low micromolar amounts of a variety of analytes in aqueous solution was developed. In particular, caffeine could be measured at a 25 $μ$M detection limit. The reported polymers are also suitable for layer-by-layer film formation.