\"Fluoro\" refers to both fluorescent and fluorinated compds. Despite the shared prefix, there are very few fluorescent mols. that are sol. in perfluorinated solvents. This paucity is surprising, given that optical microscopy is a ubiquitous technique throughout the phys. sciences and the orthogonality of fluorous materials is a commonly exploited strategy in synthetic chem., materials science, and chem. biol. We have addressed this shortage by synthesizing a panel of \"fluorofluorophores,\" fluorescent mols. contg. high wt. percent fluorine with optical properties spanning the visible spectrum. We demonstrate the utility of these fluorofluorophores by prepg. fluorescent perfluorocarbon nanoemulsions. [on SciFinder(R)]